The Steno T1 Risk Engine
Developing a screening method for cardiovascular disease in people with type 1 diabetes
Aim and purpose
Our aim is to develop a risk calculator (engine) in patients with type 1 diabetes for predicting their five- and 10-year risk of non-fatal and fatal cardiovascular disease (Ischemic heart disease, Stroke, Peripheral vascular disease).
Design and method
This study is based on detailed clinical data from the electronic health record of the approximately 5,000 patients with type 1 diabetes treated at Steno Diabetes Center. The clinical has been linked with the following Danish registers:
- National Patient Register (non-fatal cardiovascular disease events)
- Cause of Death Register (fatal cardiovascular disease events)
The risk engine has been validated on the type 1 diabetes population in the Funen (regional) Diabetes Database in Denmark.
The project targets patients with type 1 diabetes and their healthcare provider/doctor.
Expected ending is first quarter of 2016.
Subsequently, the goal is to develop an online tool free for clinicians working with type 1 diabetes. The online tool will give an individual risk profile of a patient based on his/her clinical data. In this way, the tool will support the progress towards more personalised care (individual treatment strategies) in the clinic.
Professor and chief physician, Henning Beck-Nielsen, Odense University Hospital
PhD, Jan Erik Henriksen, University of Southern Denmark
PhD, Adam Hulman, Aarhus University
Sidst opdateret 18-08-2016